Correlates of Depression and Anxiety in Acute Stroke Patients

Kim, Se Joo; Kim, Do Hoon; Choi, Nak Kyung; Kim, Hyon Chul; Moon, Yoo Sun; Kim, Hung Chul; Chung, Chan Seung

Original Article

Journal of the Korean Geriatrics Society 2003;7(3):230-242.
Published online September 30, 2003.

Correlates of Depression and Anxiety in Acute Stroke Patients

Se Joo Kim, Do Hoon Kim, Nak Kyung Choi, Hyon Chul Kim, Yoo Sun Moon, Hung Chul Kim, Chan Seung Chung

급성 뇌졸중 환자에서 우울 및 불안 증상에 영향을 미치는 요인

Abstract

BACKGROUND
This study is aimed at the pathoanatomic correlates of depression and anxiety in acute stroke patients including subcortical lesion(periventricular hyperintensity, deep white matter hyperintensity, subcortical gray matter hyperintensity).
METHODS
Sixty nine patients with acute stoke were recruited. Their brain lesions were measured using Brain MRI. Depressive or anxiety symptoms were rated by Beck depression inventory(BDI) or Beck anxiety inventory, respectively.
RESULTS
There were significant correlation between depression and periventricular hyperintensity and deep white matter hyperintensity in acute stroke patients. There are no significant pathoanatomic correla- tions between anxiety and brain lesions on MRI.
CONCLUSION
Our findings suggest that the white matter lesion may increase the risk of depression after stroke. Prevention of asymptomatic cerebrovascular lesion could decrease the risk of depression in acute stroke patients as well as the risk of stroke.

Key Words: Acute stroke, Depression, Anxiety, Brain MRI, Subcortical lesion