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Ann Geriatr Med Res > Accepted Articles
DOI:    [Accepted]
Published online April 8, 2024.
Correlation between Instrumental Activities of Daily Living and muscle mass in older adults: impact of comorbidities
M. Lucía Fernández-Millones1, Gianelli S. Curi-Vilchez1, Jose F. Parodi2, Fernando M. Runzer-Colmenares3 
1Carrera de Medicina Humana, Universidad Científica del Sur, Lima, Perú
2Universidad de San Martín de Porres, Facultad de Medicina Humana, Centro de Investigación del envejecimiento (CIEN), Lima, Perú
3CHANGE Research Working Group, Carrera de Medicina Humana, Universidad Científica del Sur, Lima,Perú
Correspondence:  Fernando M. Runzer-Colmenares,
Received: 30 January 2024   • Revised: 9 March 2024   • Accepted: 27 March 2024
There is evidence that sarcopenia and functionality are closely related. However, the association between geriatric syndromes, such as dependence, on instrumental activities and sarcopenia could be affected by the presence of certain comorbidities, such as overweight, obesity, diabetes, and chronic obstructive pulmonary disease (COPD). Therefore, the present study aimed to determine the association between instrumental activities of daily living and muscle mass in the elderly and evaluate the impact of certain comorbidities on this association.
This was a retrospective analytical observational study, including 1897 patients. Muscle mass was measured with calf circumference, and instrumental activities were measured with the Lawton index.
Among different parameters studies, a statistical correlation was found in a stratified regression analysis between the Lawton index score and muscle mass in patients who were overweight (p value:0.001 ;beta coefficient: 0.08), obese (p value: 0.001 ; beta coefficient: 0.05), had diabetes (p value: 0.012 ;beta coefficient: 0.03), and had COPD (p value:0.001 ;beta coefficient:0.03).
The correlation between muscle mass and instrumental activities of daily living should be evaluated individually according to the needs of each participant and according to their comorbidities, promoting patient-centered geriatric medicine.
Key Words: Health of the Disabled, Frail Elderly, Functional Status, Muscle, Skeletal

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