Correlation between Instrumental Activities of Daily Living and muscle mass in older adults: impact of comorbidities

Fernández-Millones, M. Lucía; Curi-Vilchez, Gianelli S.; Parodi, Jose F.; Runzer-Colmenares, Fernando M.

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Ann Geriatr Med Res > Accepted Articles

Original Article

DOI: https://doi.org/10.4235/agmr.24.0026 [Accepted]
Published online April 8, 2024.

Correlation between Instrumental Activities of Daily Living and muscle mass in older adults: impact of comorbidities

M. Lucía Fernández-Millones¹, Gianelli S. Curi-Vilchez¹, Jose F. Parodi², Fernando M. Runzer-Colmenares³

¹Carrera de Medicina Humana, Universidad Científica del Sur, Lima, Perú
²Universidad de San Martín de Porres, Facultad de Medicina Humana, Centro de Investigación del envejecimiento (CIEN), Lima, Perú
³CHANGE Research Working Group, Carrera de Medicina Humana, Universidad Científica del Sur, Lima,Perú

Correspondence: Fernando M. Runzer-Colmenares,
Email: frunzer@cientifica.edu.pe

Received: 30 January 2024 • Revised: 9 March 2024 • Accepted: 27 March 2024

Abstract

Background
There is evidence that sarcopenia and functionality are closely related. However, the association between geriatric syndromes, such as dependence, on instrumental activities and sarcopenia could be affected by the presence of certain comorbidities, such as overweight, obesity, diabetes, and chronic obstructive pulmonary disease (COPD). Therefore, the present study aimed to determine the association between instrumental activities of daily living and muscle mass in the elderly and evaluate the impact of certain comorbidities on this association.
Methods
This was a retrospective analytical observational study, including 1897 patients. Muscle mass was measured with calf circumference, and instrumental activities were measured with the Lawton index.
Results
Among different parameters studies, a statistical correlation was found in a stratified regression analysis between the Lawton index score and muscle mass in patients who were overweight (p value:0.001 ;beta coefficient: 0.08), obese (p value: 0.001 ; beta coefficient: 0.05), had diabetes (p value: 0.012 ;beta coefficient: 0.03), and had COPD (p value:0.001 ;beta coefficient:0.03).
Conclusion
The correlation between muscle mass and instrumental activities of daily living should be evaluated individually according to the needs of each participant and according to their comorbidities, promoting patient-centered geriatric medicine.

Key Words: Health of the Disabled, Frail Elderly, Functional Status, Muscle, Skeletal