| A Case of Systemic Inflammatory Response Syndrome Secondary to an Acute Polyarticular Gout |
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Ji Hyun Cheon, Ji Ung Kim, Sun Kwang Kim, Sung Hyun Ko, Jun Ho Jo, Geon Woo Park, Jin Suk Lee, Hyoung Yoel Park |
1Department of Internal Medicine, Busan Veterans Hospital, Busan, Korea. drcecil@hanmail.net
2Department of Laboratory Medicine, Busan Veterans Hospital, Busan, Korea. |
| 급성 다발성 통풍으로 인한 전신 염증 반응 증후군 1례 |
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천지현1, 김지웅1, 김선광1, 고성현1, 조준호1, 박건우1, 이진숙2, 박형열1 |
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부산보훈병원 내과1, 부산보훈병원 진단검사의학과2 |
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| Abstract |
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Gout occurs as a response to monosodium urate crystal, that is present in joints, bones and soft tissue. The classic symptoms of gouty arthritis are recurrent attacks of acute, markedly painful monoarticular or oligoarticular inflammation; but polyarthritis and chronic arthritis can also occur. Differential diagnosis from infectious arthritis is important. A definitive diagnosis requires the direct identification of urate crystals in the joint, and the exclusion of infection. We report the case of systemic inflammatory response syndrome (SIRS), developed from acute polyarticular gout. SIRS is characterized by loss of local control of inflammation, or an overly activated response resulting in an exaggerated systemic response. The SIRS was presumably due to systemic effects of a localized inflammatory response to urate crystals. |
| Key Words:
Gout, Systemic inflammatory response syndrome, Sepsis |
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