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Ann Geriatr Med Res > Volume 18(1); 2014 > Article
Journal of the Korean Geriatrics Society 2014;18(1):16-23.
DOI: https://doi.org/10.4235/jkgs.2014.18.1.16     Published online March 31, 2014.
One-Year Follow-up Pilot Study for Dementia Diagnosis in Elderly with Recall Score of 0 in Korean-version of Mini-Mental State Examination
Yun Jeong Hong, Dong Won Yang, Bora Yoon, Yong S Shim, A Hyun Cho, Il Woo Han, Myoung Sung Moon
1Department of Neurology, Yong-in Hyoja Geriatric Hospital, Yongin, Korea.
2Department of Neurology, Seoul St. Mary's Hospital, School of Medicine, The Catholic University of Korea, Seoul, Korea. neuroman@catholic.ac.kr
3Mapo-gu Regional Center for Dementia, Seoul, Korea.
4Department of Neurology, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea.
기억회상 0점 노인을 대상으로 한 1년 뒤 치매
이행률에 대한 예비 연구
홍윤정1⦁양동원2,3⦁윤보라4⦁심용수2⦁조아현2⦁한일우1⦁문명성3
용인 효자병원 신경과1, 가톨릭대학교 의과대학 서울성모병원 신경과2, 마포구 치매지원센터3, 건양대학교 의과대학 신경과학교실4
Abstract
BACKGROUND
The early stage of Alzheimer disease might show early memory impairment with normal general cognitive function. Our study aimed to investigate elderly with normal Korean version of mini-mental state examination (K-MMSE) score and recall score of 0 for 1 year. We predicted that the patients would show different characteristics and would progress more rapidly compared with normal controls.
METHODS
This study was based on the data from complete enumeration survey of Mapo-gu Regional Center for Dementia in 2009. We divided all subjects into three groups: subjects with normal K-MMSE scores and recall score of 0 were group 1-1 (n=152), subjects with abnormal K-MMSE scores were group 1-2 (n=64) and subjects with normal K-MMSE scores and recall score of 1 to 3 were group 1-3 (n=941). We compared basic demographics and social characteristics among the three groups. After 1 year (2010), the subjects in group 1-1 (90 out of 152) underwent follow-up examinations for dementia diagnosis. They were also divided into three groups (2-1, 2-2, 2-3) according to K-MMSE and recall scores.
RESULTS
Group 1-1 showed different baseline characteristics compared with normal controls. After 1 year, 25.5% (23 out of 90) of the group 2-1 were diagnosed as mild cognitive impairment (n=16) or dementia (n=7).
CONCLUSION
Our study suggested that subjects with normal K-MMSE scores but recall score of 0 are not entirely "normal". Further detailed evaluation might be needed if memory impairment is suspicious although the K-MMSE scores are within normal range.
Key Words: K-MMSE, Memory recall, Enumeration survey, Dementia
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