| The Effect of Aging on the Hemodynamic Response to Endotracheal Intubation during the Induction of Anesthesia |
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Myoung Keun Shin, Wang Gyu Lee, Haeng Seon Shim |
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Department of Anesthesiology and Pain Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea. 6512hs@naver.com |
| 전신마취 유도 시 기관 내 삽관의 나이 변화에 따른 혈역학적 반응 비교 |
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신명근⦁이왕규⦁심행선 |
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성균관대학교 의과대학 삼성창원병원 마취통증의학교실 |
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| Abstract |
BACKGROUND
The aim of this study was to evaluate the effect of aging on the hemodynamic response to endotracheal intubation during the induction of anesthesia.
METHODS
Fifty patients with American Society of Anesthesiologists physical status classification 1 or 2 were enrolled and allocated according to age to either group N (35-44 years, not elderly, n=25) or group E (65-74 years, elderly, n=25). The patients were administered 3 minimum alveolar concentrations of sevoflurane for 5 minutes for the induction of anesthesia. Systolic arterial pressure (SAP) and heart rate (HR) were recorded before (baseline), immediately after (T0), and at 1-minute intervals during the first 4 minutes after endotracheal intubation (T1-T4).
RESULTS
SAP increased by 15.4% and 10.8%(p<0.05) from the baseline at T0 and T1, respectively, in group N, and by 21.6%, 17.8%, and 11.8%(p<0.05) from the baseline at T0, T1 and T2 respectively, in group E. The SAP increases at T0, T1 and T2 were significantly greater in group E than in group N (p<0.05). The HR increases at T0 and T1 were significantly greater for group N than for group E (p<0.05).
CONCLUSION
We recommend that anesthesiologists vigilantly monitor and attenuate adverse hemodynamic responses for at least 5 minutes after endotracheal intubation especially in elderly patients, particularly because significant systolic hypertension can occur in this age group. |
| Key Words:
Elderly, Hemodynamic, Intubation, Sevoflurane |
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