Ann Geriatr Med Res Search

CLOSE


Ann Geriatr Med Res > Volume 21(2); 2017 > Article
Annals of Geriatric Medicine and Research 2017;21(2):70-77.
DOI: https://doi.org/10.4235/agmr.2017.21.2.70    Published online June 30, 2017.
Weight Status and All-Cause Mortality in Older Adults: A Study of Patients With Type 2 Diabetes Undergoing Subtotal Gastrectomy for Cancer
Yeongkeun Kwon, Kyeong Jin Kim, Yong Kyun Roh, Yong Gyu Park, Sungsoo Park, Kyung Hwan Cho
1Division of Geriatrics, Department of Family Medicine, Korea University College of Medicine, Seoul, Korea. chokh@korea.ac.kr
2Center for Obesity and Metabolic Diseases, Korea University Anam Hospital, Seoul, Korea. kugspss@korea.ac.kr
3Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
4Department of Family Medicine, Hallym University College of Medicine, Chuncheon, Korea.
5Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul, Korea.
6Division of Upper Gastrointestinal Surgery, Department of Surgery, Korea University College of Medicine, Seoul, Korea.
Correspondence:  Kyung Hwan Cho,
Email: chokh@korea.ac.kr
Abstract
BACKGROUND
The survival benefit of excess body weight is controversial across various subpopulations. We assessed the effect of weight status on all-cause mortality among patients with type 2 diabetes (T2DM) undergoing subtotal gastrectomy for gastric cancer.
METHODS
Medical charts of 210 patients with T2DM treated at 2 university hospitals were examined retrospectively. All patients had undergone subtotal gastrectomy for cancer between January 1993 and December 2012. Participants were categorized as normal weight (body mass index [BMI], 18.5–24.99 kg/m²) or overweight/obese (BMI≥25 kg/m²). The association between weight status and all-cause mortality was assessed using weighted Cox proportional hazard regression models and inverse probability weighting.
RESULTS
The mortality rate was 25.2% after a median follow-up duration of 6.1 years (interquartile range, 3.5–8.3 years; maximum, 14.4 years). The overweight/obese group had a significantly lower risk of all-cause mortality (hazard ratio, 0.51; 95% confidence interval, 0.34–0.77; p=0.001) compared with the normal weight group. Overweight/obesity was associated with reduced all-cause mortality in patients aged <65 years (p=0.01 for interaction).
CONCLUSION
Among T2DM patients who underwent subtotal gastrectomy for cancer, only the subgroup of patients aged <65 years in the overweight/obese group showed reduced all-cause mortality compared with the normal weight group.
Key Words: Type 2 diabetes, Body mass index, Subtotal gastrectomy, Stomach neoplasms, Mortality


ABOUT
ARTICLE & TOPICS
Article Category

Browse all articles >

TOPICS

Browse all articles >

BROWSE ARTICLES
EDITORIAL POLICY
FOR CONTRIBUTORS
Editorial Office
#401 Yuksam Hyundai Venturetel, 20, Teheran-ro 25-gil, Gangnam-gu, Seoul 06132, Korea
Tel: +82-2-2269-1039    Fax: +82-2-2269-1040    E-mail: agmr.editorial@gmail.com                

Copyright © 2022 by Korean Geriatrics Society.

Developed in M2PI

Close layer
prev next