| Changes on Cognitive Function after Carotid Artery Stenting in Patients with Severe Carotid Artery Stenosis: A Prospective, 3 Months Follow-up Study |
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Ji Yoon Kang, Hye Suk Kim, Myung Jin Kang, Dae Hyun Kim, Jae Kwan Cha, Jae Tack Huh, Jae Woo Kim, Kyung Won Park |
1Department of Neurology, Dong-A University College of Medicine, Busan, Korea. neuropark@dau.ac.kr
2Busan-Ulsan Regional Cardiocerebrovascular Center, Busan, Korea. |
| 심한 경동맥 협착증 환자에서 경동맥 스텐트 시술 전, 후의 인지기능 변화: 전향적 관찰 연구 |
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강지윤1 · 김혜숙1 · 강명진2 · 김대현1 , 2 · 차재관1, 2 · 허재택2 · 김재우1 · 박경원1 |
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1동아대학교 의과대학 신경과학교실, 2부산·울산 권역 심뇌혈관센터 |
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| Abstract |
BACKGROUND
Carotid artery stenting (CAS) is emerging as an alternative to carotid endarterectomy for the treatment of carotid stenosis. The effects of CAS on cognitive function have not been fully addressed. The aim of this study was to assess the effect of carotid stenting on cognitive function from baseline to 3 months in patients with severe carotid artery stenosis through the use of a detailed neuropsychological test.
METHODS
We recruited 28 patients with carotid artery stenosis (> or =70%) at baseline on a consecutive basis between February, 2009 and December, 2010. Twenty-two patients out of 28 cases, who had undergone CAS and follow-up neuropsychological evaluation after 3 months, were included in our analysis. Main cognitive outcome measures were the Seoul Neuropsychological Screening Battery-Dementia version (SNSB-D), which containing detailed cognitive tasks. We evaluated the baseline clinical characteristics and changes of cognitive outcome measures using SNSB-D in our cases from baseline to 3 months follow-up period, respectively.
RESULTS
After a 3 month follow-up period, patients that underwent CAS showed significant improvement in cognitive function in total SNSB-D score compared to the baseline state of 18.1 points at 3 months (p<0.05). The other cognitive outcome measures showed significant improvements (p<0.05) in the task of confrontational naming, visual memory, and the scale of clinical dementia rating sum of box.
CONCLUSION
We found that there might be a positive effect of carotid artery stenting on cognitive function from baseline to 3 months in patients with severe carotid artery stenosis. |
| Key Words:
Carotid stenosis, Stent, Cognition, Neuropsychological test |
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