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Journal of the Korean Geriatrics Society 1999;3(4):50-55.
Published online December 31, 1999.
Inappropriate Secretion of Antidiuretic Hormone in a Patient with Squamous Cell Carcinoma of the Lung mimicking Pulmonary Tuberculosis
Soon Je Kim, Ha Keun Ryu, Sun Doo Kim, Kil Do Lee, Bong An Park, Ju Seong Ryu, Jae Deung Yu
Department of Internal Medicine and Radiology KonKuk University College of Medicine, Chungj u, Korea
폐결핵으로 오인된 SIADH를 동반한 편평상피 세포폐암 1예
Abstract
A 71-year-old man with squamous cell carcinoma of lung mimicking pulmonary tuberculosis associated with the syndrome of inappropriate secretion of ADH(SIADH). Laboratory examination showed serum sodium concentration of 108 mEq/l. serum osmolality 247 mEg/l urine sodium concentration of 141 mEq/l urine osmolality 547 mEq/l. normal levels (<0.56 pg/ml) of serum antidiuretic hormone (ADH). ADH release was regulated normally with changes in serum osmolality. SIADH was diagnosed on the basis of hyponatremia with corresponding serum hypoosmolality and a high urine osmolality due to continuous sodium excretion. In this case, SIADH was probably induced by increased renal sensitivity to ADH and suspected high serum ANP level of unknown origin.
Key Words: SIADH, Squamous cell carcinoma of the lung, ADH, ANP
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