Inappropriate Secretion of Antidiuretic Hormone in a Patient with Squamous Cell Carcinoma of the Lung mimicking Pulmonary Tuberculosis |
Soon Je Kim, Ha Keun Ryu, Sun Doo Kim, Kil Do Lee, Bong An Park, Ju Seong Ryu, Jae Deung Yu |
Department of Internal Medicine and Radiology KonKuk University College of Medicine, Chungj u, Korea |
폐결핵으로 오인된 SIADH를 동반한 편평상피 세포폐암 1예 |
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Abstract |
A 71-year-old man with squamous cell carcinoma of lung mimicking pulmonary tuberculosis associated with the syndrome of inappropriate secretion of ADH(SIADH). Laboratory examination showed serum sodium concentration of 108 mEq/l. serum osmolality 247 mEg/l urine sodium concentration of 141 mEq/l urine osmolality 547 mEq/l. normal levels (<0.56 pg/ml) of serum antidiuretic hormone (ADH). ADH release was regulated normally with changes in serum osmolality. SIADH was diagnosed on the basis of hyponatremia with corresponding serum hypoosmolality and a high urine osmolality due to continuous sodium excretion. In this case, SIADH was probably induced by increased renal sensitivity to ADH and suspected high serum ANP level of unknown origin. |
Key Words:
SIADH, Squamous cell carcinoma of the lung, ADH, ANP |
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