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Ann Geriatr Med Res > Volume 16(3); 2012 > Article
Journal of the Korean Geriatrics Society 2012;16(3):149-152.
DOI: https://doi.org/10.4235/jkgs.2012.16.3.149    Published online September 30, 2012.
A Patient with Distinct Evidences of Spontaneous Regression and Recurrence of Gastric Cancer for 13 Years
Seong Eun Yang, Yun Jung Lee, Jin A Lee, Sae Hee Kim, Sung Hee Jung, Anna Kim, Hyeongkug Kim, Hyun Jin Moon, Yong Hun Choi
Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea. yjlee@eulji.ac.kr
13년간 반복적인 자연 완화와 재발을 보인 위암 환자
양성은1, 이윤정1, 이진아1, 김새희1, 정성희1, 김안나1, 김형국1, 문현진1, 최용훈1
을지대학교 을지대학병원 내과학교실
Abstract
Spontaneous regression (SR) of malignancy is a rare phenomenon, especially in patients with gastric cancer. A 77-year-old male, who was already diagnosed with gastric adenocarcinoma by endoscopic biopsy from a private clinic, was referred to our hospital. Despite our strong recommendation, the patient refused surgical therapy. A follow-up endoscopy was performed 3 months later, which revealed that the ulcer had changed into a white scar. Endoscopic biopsy revealed only chronic inflammation. Two and 6 years later, cancer recurred, and SR was confirmed both times, histologically, at the gastric body. The patient is still alive without any gastrointestinal symptoms after 13 years of follow-up. The cause of SR is yet uncertain and there are only a few suggestions of scientific mechanisms. We, herein, report this very rare case of repeated recurrence and SR of gastric cancer without clear cause.
Key Words: Spontaneous neoplasm regression, Neoplasm recur, Gastric cancer
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