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Ann Geriatr Med Res > Volume 18(1); 2014 > Article
Journal of the Korean Geriatrics Society 2014;18(1):39-43.
DOI: https://doi.org/10.4235/jkgs.2014.18.1.39     Published online March 31, 2014.
Thrombotic Thrombocytopenic Purpura and Rhabdomyolysis Associated With Acute Renal Failure in Hypothyroidism
Jeonghun Lee, Kang Woo Lee, Sung Min Yun, Hyun Chun Shin, Soo Min Nam, Nam Yeol Cho
Department of Internal Medicine, Daejeon Sun Hospital, Daejeon, Korea. endokwlee@gmail.com
갑상선기능저하증에서 발생된 혈전혈소판감소자색반병과
급성신부전을 동반한 횡문근융해 1예
대전 선병원 내과
Myopathy due to hypothyroidism can be detected in its early stage, but as the symptom is mild, complications such as rhabdomyolysis are rare. Thrombotic thrombocytopenic purpura in hypothyroidism is not yet clearly defined, and rare cases of it are reported. Reported herein is a case of thrombotic thrombocytopenic purpura and rhabdomyolysis associated with acute renal failure in hypothyroidism. A 70-year-old male was admitted to the hospital due to general weakness and muscle pain. Later, based on the laboratory findings, he was diagnosed with rhabdomyolysis associated with acute renal failure and thrombotic thrombocytopenic purpura combined with hypothyroidism. Initially, he was treated with fluid resuscitation due to rhabdomyolysis combined with acute renal failure but eventually, the levothyroxine supplement lowered the thyrotropin-stimulating hormone level. As a result, the patient recovered from rhabdomyolysis and thrombotic thrombocytopenic purpura without receiving plasmapheresis treatment.
Key Words: Hypothyroidism, Rhabdomyolysis, Thrombotic thrombocytopenic purpura
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