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Journal of the Korean Geriatrics Society 2008;12(1):24-29.
Published online March 31, 2008.
A Safety and Effectiveness of High Pressure Balloon Dilatation for Sirolimus-Eluting Stent Implantation in the Ischemic Heart Disease
Seung Eun Lee, Woo Hyung Bae, Nam Sik Kim, Sung Han Yun, Han Cheol Lee, Jun Kim, June Hong Kim, Kook Jin Chun, Taek Jong Hong, Yung Woo Shin
허혈성 심질환 환자에서 Sirolimus 용출성 스텐트 삽입술시 과확장의 안전성과 효과
Abstract
BACKGROUND
We have no information about the safety and effectiveness when we perform overdilating a sirolimuseluting stent(SES) with high pressure. In some specific animal model, the study reported overdilatation of SES with high pressure resulted in increase of restenosis. The aim of this study was to evaluate the safety and effectiveness of overdilatation of SES with high pressure.
METHODS
97 patients underwent PCI using SES between August 2003 and July 2005 were divided into two group(high pressure group, low pressure group), stents were implanted with high pressure(>18 atm) and low pressure(<12 atm). We compared between the two group of safety of stents, major adverse cardiac events(MACE), rate of restenosis, late loss.
RESULTS
In high pressure group, there are more type C lesion(51% vs 38%, p<0.01). There were no significant differences between the two groups regarding MACE(12.8% vs 17.2%, p=0.78), in-stent restenosis rate(2.6 % vs 5.2%, p=0.65). There are small increasing of late loss in high pressure group, but no statistically significant difference(0.30 vs 0.15, p=0.05).
CONCLUSION
Implantation of SES overdilated with high pressure is able to be performed safely to obtain wider inner lumen of stents.
Key Words: Sirolimus-eluting stent, High pressure, Overdilatation
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