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Journal of the Korean Geriatrics Society 2004;8(3):182-185.
Published online September 30, 2004.
A Case of Brain Stem Neuro-Behcet's Disease Presenting as Paroxysmal Headache With Autonomic Features
Yong Seok Choi, Jung Mee Kim, Young Su Han, Jeong Seon Cho, Jeong Ho Han, Eun Kyoung Cho, Doo Eung Kim
Department of Neurology, Seoul Veterans Hospital , Seoul , Korea. yongsaek@hanmail.net
자율신경증상의 발작성 두통을 주소로 내원한 뇌간병변 신경베체트병 1예
Migraine without aura was significantly frequent in Beh et's disease patients. While, the relationship of TAC(trigeminal autonomic cephalalgia) and Beh et's disease was not known. And, it is thought that pathogenesis of proxysmal headache with autonomic features in neuroBehcet's disease as our case may be different from those of clust headache and TAC. A 45-year-old male admitted with left sided periobital poxysmal headache accompained by ipsilateral conjunctival injection and lacrimination with autonomic features. T2WMR image showed about 1.5x2.6x2.6 cm sized mass with high signal intensity surrounded by a rim of low signal intensity in pons. Enhanced MR image showed enhancing mass-like lesion inside the T2 high signal intensity. CSF study revealed neutrophilic pleocytosis with normal pressure, protein and glucose concentration. No malignant cell were seen. Antiphospholipid antibody and cryoglobuline was significantly increased. 3 days after hospitalvisit, oral ulcerations appeared in the patient. He was treated with high-dose steroid for a week and his headache and abnormal findings of CSF study became fully recovered. Two weeks later, the mass was nearly reduced in the pons on follow-up MR image. We suggest to include a careful interviewfor 2ndary TAC as the first neurologic symptom in the diagnostic work-up of Behet's disease.
Key Words: Neuro-Beh et's disease, Trigeminal autonomic cephalalgia
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