A Reversible Posterior Leukoencephalopathy Syndrome

Kim, Don Soo; Kim, Yong Duk; Choi, Young Chul

Original Article

Journal of the Korean Geriatrics Society 2001;5(2):196-199.
Published online June 30, 2001.

A Reversible Posterior Leukoencephalopathy Syndrome

Don Soo Kim, Yong Duk Kim, Young Chul Choi

가역성 후두부 뇌백질병증 증후군

Abstract

Reversible posterior leukonecephalopathy syndrome RPLS), a neurologie disorder associated with evidence of posterior cerebral edema on neuroimaging studies, has been described in both adults and children. Conditions predisposing to RPLS include malignant hypertension, renal dysfunction, toxemia of pregnancy, interferon therapy, and the use of immunosuppressive agents. When associated with acute hypertension, RPLS typically occurs concurrently with the fulminant clinical syndrome of hypertensive encephalopathy We describe occipital lobe seizures, in the setting of only moderate elevations of blood pressure, as the major clinical manifestation of RPLS.

Key Words: Reversible posterior leukoencephaiopathy, Hypertensive encephlaopathy, Occipital lobe seizure

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