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Tu, Lin, Hsu, and Wu: High Mortality and Medical Costs in Geriatric Trauma Patients: Surgical Treatment and Risk Factors from a Retrospective Cohort Study at a Level I Trauma Center

Abstract

Background

Trauma remains a leading cause of death and disability. With the rapidly growing aging population, geriatric patients face heightened trauma risks due to physiological decline and comorbidities. Despite the growing burden, data on the clinical characteristics, injury mechanisms, patterns, and healthcare utilization in this group remain limited. This study analyzed trauma outcomes and associated factors in geriatric patients.

Methods

We conducted a retrospective cohort study using data from a Level I trauma center. Patients aged ≥65 years were compared with younger adults (<65 years). Variables included demographics, injury mechanism, Glasgow Coma Scale (GCS), Revised Trauma Score (RTS), Abbreviated Injury Scale (AIS), Injury SeverityScore (ISS), clinical outcomes, and medical costs. Multivariate logistic regression identified mortality predictors.

Results

Among 10,358 trauma patients with mean age of 54.2 years, 61.9% of younger patients were male, compared to 37.7% in the geriatric group (p<0.001). Geriatric patients exhibited lower male predominance, higher costs, and greater mortality (p<0.001). Multivariable analysis revealed that, among geriatric groups, male sex, older age, lower GCS, lower RTS, burns injuries, and severe injuries (AIS ≥3) to head, thoracic, extremity, and appearance were significant mortality predictors. Undergoing orthopedic and thoracic surgeries was associated with lower mortality in geriatric patients.

Conclusion

Geriatric trauma patients experience higher mortality risks and demands. Timely interventions, critical care management, appropriate triage, and age-adapted assessment tools are essential for improving clinical outcomes. These findings underscore the importance of interdisciplinary care strategies to optimize geriatric trauma management and resource utilization.

INTRODUCTION

Trauma is a major global health issue. According to the World Health Organization, it causes around 4.4 million deaths annually, accounting for nearly 8% of all global fatalities. Additionally, trauma contributes to an estimated 10% of all years lived with disability, significantly impacting individuals and societies globally.1) With advancements in medical care, the aging population has grown rapidly. The proportion of older adults worldwide is projected to increase from 12% in 2015 to 22% by 2050.2) This demographic shift is primarily due to decreased disease-specific mortality and increased life expectancy.3) In Taiwan, the proportion of people aged ≥65 years reached 19.6% in July 2025,4) placing the country on the verge of becoming a super-aged society. The current life expectancy is 84.3 years for women and 77.4 years for men.5) Geriatric patients are particularly vulnerable to trauma, accident-related injuries being the most common among in this age group.6) These trends highlight the urgent need to address the unique challenges associated with aging populations and trauma care.
Previous reports indicate significant differences in injury mechanisms and patterns between older and younger individuals.7) Compared to younger patients, geriatric individuals have reduced physiological reserves and lower pre-injury functional capacities, making older age an independent risk factor for trauma mortality.8) Age-related physiological changes and chronic comorbidities further complicate trauma care in older adults, contributing to increased healthcare resource utilization and higher mortality.9) The aging population increases the burden on trauma systems and long-term care resources.10) Optimal trauma management through geriatric early diagnosis, effective treatment, and rehabilitation can improve quality of life, reduce mortality, and alleviate economic burdens.11,12)
The clinical characteristics and cost patterns of geriatric trauma in East Asian populations remain underexplored. This study addresses these gaps by conducting a retrospective cohort analysis to examine the demographics, injury characteristics, mechanisms, clinical outcomes, and expenditure categories among trauma patients, with a focus on geriatric individuals. The findings aim to inform healthcare strategies and improve trauma care preparedness for aging populations.

MATERIALS AND METHODS

Study Setting

This retrospective cohort study was conducted at a Level I trauma center in Taiwan. Data were obtained from a prospectively maintained institutional trauma registry. The registry includes patients who presented to the emergency department and were either admitted to the hospital or underwent trauma team activation. Patients admitted between January 1, 2017, and July 31, 2022 were included, excluding those injured more than 14 days prior to admission. This study was approved by the Institutional Review Board of National Taiwan University Hospital (Approval No. 202311009RINC).

Data Collection and Outcome Measures

The collected data were categorized into demographics, injury severity, mechanism of injury, clinical outcomes, and hospitalization costs. Costs were presented in US dollar (USD), converted using an average exchange rate of 1 USD=29.78 New Taiwan dollars (TWD), based on data from January 2017 to July 2022.
Geriatric patients were defined as those aged ≥65 years.13) Injury severity was assessed using the Glasgow Coma Scale (GCS), Revised Trauma Score (RTS), Abbreviated Injury Scale (AIS), and Injury Severity Score (ISS). The GCS categorized injuries as severe (3–8), moderate (9–12), or minor (13–15).14) RTS was calculated using systolic blood pressure, respiratory rate, and GCS with a total score ranging from 0 (worst) to 7.8 (best).15) AIS classified injuries into six body regions, with severe injuries defined as AIS ≥3.16) ISS categorized injuries as minor (0–15), moderate (16–24), or severe (≥25).17) Mortality (primary outcome) was defined as in-hospital death during the index admission (including emergency department deaths).

Statistical Analysis

Continuous variables (e.g., age, revised trauma score, and cost) were analyzed with independent sample t-tests and reported as mean±standard deviation, while categorical variables (e.g., sex and GCS) were analyzed using chi-square tests and reported as frequency (%). Tables 1 and 2 summarize total expenditure comparisons by age group and in-hospital mortality, respectively. For the medical cost variable, cases with missing data were excluded. These exclusions were primarily due to emergency deaths, observation discharges, or missing billing records. Detailed category-specific costs are presented in Supplementary Tables S1 and S2, but were not included in the mortality model due to their post-admission nature and potential reverse causality. Furthermore, we assessed the association between clinical factors and the risk of in-hospital mortality using logistic regression models, separated by age group (<65 vs. ≥65 years). In the first step, a series of univariate logistic models was conducted to identify possible associated factors. Secondly, those variables with a p-value less than 0.15 in the univariate analyses were included in the multivariable logistic model to adjust for potential confounders. ISS was excluded from the multivariable model due to collinearity with the severe injury variables (e.g., head, face, and thoracic). All tests were two-tailed, and p<0.05 was considered statistically significant. Data analyses were conducted using SPSS version 26 (IBM SPSS Inc., Armonk, NY, USA).

RESULT

Characteristics of Patients in Younger and Geriatric Adults

The detailed baseline and clinical characteristics are summarized in Table 1. A total of 10,358 patients were included, with a mean age of 54.2±24.4 years; 59.9% were younger adults, and 40.1% were older adults. Overall, 52.2% of the patients were male. The majority of patients (92.4%) had an initial GCS score of 13–15, and 83.0% had an ISS between 0–15. Falls were the most common mechanism of injury (53.7%). The mean hospital stay was 8.5 days, with 19.3% of patients requiring intensive care unit (ICU) care. A total of 81.2% of patients underwent surgery, with orthopedic procedures comprising the majority (64.8%). Complications occurred in 9.2% of cases. The overall in-hospital mortality rate was 3.6%, and the mean hospitalization cost was USD 3,349±7,450, with a range of 70–317,928.
Compared to younger adults, older adults had fewer males (37.7%), higher rates of moderate GCS (9–12), and falls (all p<0.001). Geriatric patients with severe ISS (≥25) more frequently sustained severe injuries to the extremities and head (AIS ≥3). They also had longer hospital stays, higher ICU admissions, more complications, and significantly higher mortality. Older adults had a higher RTS than younger adults (7.6 vs. 7.5; p=0.006). Younger adults underwent more surgeries overall, whereas older adults had a higher proportion of orthopedic and neurosurgical procedures. Among geriatric patients, non-surgical hospitalization costs were significantly higher across all categories (p<0.001) (Supplementary Table S1).

Characteristics of Patients in Younger and Geriatric Adults Stratified by In-hospital Mortality

The analysis of 375 deaths in younger and geriatric adults is summarized in Table 2. Indicators of injury severity (GCS, RTS, and ISS) were worse in younger adults. In cases of severe injury, head injury was the leading cause of mortality in both younger and older patients. In terms of mechanism of injury, falls (62.9%) and traffic accidents (25.2%) were the leading causes among geriatric adults, while suicide (34.5%) and traffic accidents (33.9%) were the primary causes among younger adults. Older adults had longer hospital stays, required more ICU care, experienced more complications, and underwent surgical interventions—particularly neurosurgical (19.0%) and orthopedic procedures (11.4%). Among geriatric patients, hospitalization costs were significantly higher across all categories except surgical fees (p<0.001) (Supplementary Table S2).

Predictors of Mortality in Younger Adults and Geriatric Patients

In the younger adult group (<65 years), several factors were significantly associated with increased mortality. These included older age (adjusted odds ratio [aOR]=1.03, 95% confidence interval [CI] 1.01–1.04), lower GCS (≤8) (aOR=14.10, 95% CI 5.38–36.92) and GCS 9–12 (aOR=7.18, 95% CI 2.88–17.91), and lower RTS (aOR=0.57, 95% CI 0.49–0.65). The presence of severe thoracic and extremity injuries, falls, and suicide was also associated with higher mortality. Conversely, patients undergoing neurosurgery (aOR=0.32, 95% CI 0.15–0.68), plastic surgery (aOR=0.11, 95% CI 0.02–0.53), or orthopedic surgery (aOR=0.01, 95% CI 0.004–0.06) had significantly lower mortality (Table 3, Fig. 1).
In the geriatric group (≥65 years), male sex and older age were independently associated with higher mortality. Similar to the younger group, lower GCS scores (≤8) (aOR=7.33, 95% CI 3.69–14.57) and lower RTS (aOR=0.73, 95% CI 0.63–0.84) were significantly associated with mortality. Severe head, thoracic, extremity, and appearance injuries also showed strong associations with increased mortality. Burn injuries also showed a significant correlation with increased mortality in this group (aOR=2.57, 95% CI 1.004–6.57). Mortality was significantly lower in geriatric patients undergoing orthopedic and thoracic surgeries (aOR=0.09, 95% CI 0.04–0.21 and aOR=0.21, 95% CI 0.07–0.63, respectively) comparing to other surgical interventions (Table 3, Fig. 1). The details of univariate logistic analyses were shown in the supplements (Supplementary Table S3).

DISCUSSION

This study provides a comprehensive analysis of demographics, injury mechanisms, severity patterns, clinical outcomes, and expenditure categories in both younger and geriatric trauma patients, aiming to address key gaps in understanding their care needs. Consistent with previous research, our findings confirm that older age is an independent predictor of mortality, even after adjusting for injury type and severity in geriatric trauma patients.8,18) Age ≥65 years represents a clinically significant threshold, as geriatric trauma patients have been shown to experience a threefold higher in-hospital mortality rate compared to younger adults.19) Older patients are particularly difficult to triage due to the lack of reliable indicators for injury severity and physiological reserve. As a result, they are frequently undertriaged, which contributes to increased risks of mortality and post-discharge disability.19) In addition, comorbidities are more prevalent in this population, further complicating clinical management and outcomes. Geriatric patients often present with complex needs and demand greater medical resources, which makes their management particularly challenging.10) These findings suggest that older trauma patients should be recognized as a group with unique care needs. A better understanding of age-related differences in injury patterns, clinical management, and outcomes could support the development of more effective and age-adapted care strategies that address the diverse and complex needs of the geriatric population.
Additionally, this study identified male sex as an independent predictor of mortality among older trauma patients, even though women constituted the majority of geriatric trauma cases. Although the association between sex and trauma-related mortality remains controversial, similar patterns have also been observed in trauma subgroups. Biological factors may contribute to this difference. Men often exhibit weaker clot formation and strength after trauma, and when coagulopathy is present, they have higher mortality than women.20) Females after trauma show lower mortality and better functional outcomes, which may be related to differences in immune response, inflammatory regulation, and the protective effects of sex hormones.21) A retrospective cohort study from Japan found that women with post-traumatic sepsis had lower in-hospital mortality than men, possibly due to the protective effects of estrogen on immunity and coagulation, genetics, and healthcare-related. This survival advantage persisted among patients aged ≥65 years.22) Some studies have shown that higher mortality in men relates to injury mechanisms. Men have higher mortality in high-energy incidents, such as motor vehicle collisions or falls.23-25) An exploratory comparison between older male and female trauma patients using available registry variables is provided in Supplementary Table S4. These additional data highlight differences in injury severity, mechanisms, anatomical distribution, and clinical outcomes, but were not part of the predefined objectives of this study. These findings suggest that sex-related differences in post-trauma outcomes should be considered in clinical evaluation and care planning. This association may be partially explained by differences in injury mechanisms, physiological responses, or comorbidity profiles between sexes. Further investigation is suggested for future studies.
Previous studies have shown that falls are the leading cause of mortality among older trauma patients.8,16) Among geriatric trauma patients in our study, falls were the most common mechanism (77.3%), followed by traffic accidents (16.6%). However, multivariable regression revealed that burn injuries are a significant mechanism of mortality in older patients. In our analysis, burn injuries were independently associated with an increased risk of in-hospital mortality (aOR=2.57, 95% CI 1.004–6.57). This may reflect differences in injury severity or healthcare response and shows the importance of recognizing burns as a high-risk injury. Burns were less frequent but showed high fatality in older adults.26) Similarly, Stanojcic et al.27) found that even small burns led to excess deaths in older patients due to delayed immune response and impaired inflammatory regulation. Furthermore, Cords et al.28) found a 12% in-hospital mortality rate and tenfold increase in long-term mortality for patients aged 65–74. These findings suggest that age-related frailty and reduced physiological reserve may drive burn-related mortality, rather than burn size alone.28,29) While burn extent and depth are often visually apparent, standard triage tools may underestimate mortality risk in older patients. Therefore, age-adapted evaluation frameworks that incorporate adaptive capacity and frailty indicators are essential for improving risk prediction and timely intervention. These findings emphasize the need for greater clinical attention in the care of geriatric trauma patients. Although burn injuries are relatively uncommon in this population, their high mortality rate deserves particular focus. Early identification of high-risk patients and appropriate resuscitation measures, such as fluid replacement and airway management, are essential. A multidisciplinary approach involving trauma surgeons, burn specialists, and geriatric care teams may further improve outcomes through coordinated and individualized care plans. In addition, implementing dedicated burn care and rehabilitation plans may help improve outcomes in older adults affected by this mechanism of injury.
Our study found that both GCS ≤8 (aOR=7.33) and RTS (aOR=0.73) were significant predictors of mortality in geriatric trauma patients. Although RTS includes GCS, the two scoring systems represent different clinical aspects. GCS reflects neurological status, while RTS combines GCS, blood pressure, and respiratory rate to indicate overall physiological stability. Both scores were strongly associated with mortality, showing that poor neurological function and physiological instability are key risk factors in these groups.8,18,30) In our study, geriatric patients often arrived at the emergency department with well-preserved RTS scores, suggesting mild injuries and stable vital signs. However, among those who died, older patients had lower injury severity scores than younger patients who died, yet the mortality rate among geriatric patients was higher. This observation suggests that older adults experience worse outcomes despite less severe injuries, likely due to an impaired ability to respond to physiological stress and multiple comorbidities.7,16) This aligns with previous findings indicating that any complication can independently increase mortality in geriatric trauma, with the impact magnified by age and injury severity. This discrepancy is attributed to the reduced physiological reserve and atypical presentation in older adults, which may mask the true severity of injuries in conventional scoring systems. These findings suggest that current assessment tools may have limitations in identifying risk among geriatric trauma patients, especially those who present with stable vital signs but are physiologically vulnerable. This could lead to under-triage and delayed treatment, potentially affecting clinical outcomes. Developing age-adapted evaluation tools may help improve early recognition and timely intervention in this geriatric population.
Our study found that orthopedic and thoracic surgical interventions were significantly associated with lower in-hospital mortality among geriatric trauma patients. However, relatively few studies have examined the association between specific surgical procedures and mortality outcomes in this population. Some studies have shown that early hip fracture surgery reduces postoperative mortality31,32) and improves short-and long-term survival through early ambulation in older adults.33) Other research also supports the benefits of timely surgical intervention and early mobilization in improving recovery and reducing complications after orthopedic surgery.34,35) A previous study has shown that rib fractures in older adults (age ≥45) have been associated with increased morbidity, including longer ICU stays and higher ventilator requirements.36) More recently, studies have suggested that rib fixation in selected older patients with chest trauma may improve pain control, respiratory function, reduce complications, and potentially lower mortality.37) Similar benefits in terms of pain relief and functional recovery have also been reported in the general trauma population.38) These findings support the potential clinical value of timely orthopedic and thoracic surgical procedures in reducing mortality and promoting long-term recovery in geriatric trauma. Early surgical management may mitigate the risks of postoperative complications, promote faster mobilization, and preserve respiratory function, all of which are critical factors in this vulnerable population. Future research should explore the optimal timing, patient selection criteria and effectiveness of surgical interventions in geriatric trauma care and timely procedures should be considered as part of standard care.
Our findings indicate that the costs associated with geriatric trauma patients were significantly higher across most categories. With the exception of surgical cost, the increased expenditure among older trauma patients can be attributable to longer hospital stays, higher ICU admission rates, more severe injuries, a greater prevalence of comorbidities and complications, and the need for more extensive medical care. Such care often involves additional equipment, assistive devices, medications, and acute critical care management.39,40) These findings indicate that geriatric trauma patients have higher medical costs, placing a heavy burden on families and society. To address this challenge, planning and allocation of healthcare resources are essential. It is necessary to develop care strategies tailored to the older adults in order to maintain the quality of care while ensuring cost-effective use of medical resources.
This study has several limitations. First, data were collected from a single urban Level I trauma center, which may limit the generalizability of the findings to rural settings with different trauma care resources and may not fully represent nationwide trauma care patterns. Second, the retrospective design may be subject to selection bias and unmeasured confounding. Third, registry constraints precluded adjustment for geriatric factors, including comorbidity burden, frailty, and pre-injury functional status. Therefore, residual confounding may remain. Fourth, our cost analysis was descriptive and did not involve multivariable adjustment or length-of-stay normalization. This approach was chosen to avoid post-treatment bias, including potential reverse causality, but it may limit the interpretation of cost comparisons. Future research should explore the impact of timely surgical interventions and the role of geriatric-specific assessment tools on trauma outcomes in older adults.
In conclusion, this study demonstrates the distinct clinical and resource challenges associated with geriatric trauma. Compared to younger adults, older trauma patients experience higher mortality. Older age, male sex, poor GCS scores, and lower RTS scores were key predictors of mortality. Injuries such as burns and severe head, thoracic, or extremity trauma tended to result in poorer outcomes in older patients. In contrast, orthopedic and thoracic surgical interventions were associated with significantly lower in-hospital mortality. With global aging trends, early identification of high-risk geriatric trauma patients is essential. Age-sensitive evaluation tools, integrated surgical strategies, and interdisciplinary care models may help improve clinical outcomes while ensuring more efficient use of medical resources in this geriatric trauma population.

ACKNOWLEDGMENTS

We thank the staff of the Trauma Registry Center at NTUH for data support.

Preliminary findings from this study were presented as a poster at the 26th East Asian Forum of Nursing Scholars (EAFONS), Tokyo, Japan, 2023.

Thanks to Raising Statistics consultants for their statistical assistance with this study.

The authors sincerely appreciate the support for the article processing charge provided by the Department of Traumatology, National Taiwan University Hospital, and the National Taiwan University Hospital intramural research project (Grant No. 113-0291).

CONFLICT OF INTEREST

The researchers claim no conflicts of interest.

FUNDING

None.

AUTHOR CONTRIBUTIONS

Conceptualization, THL, HRT; Data curation, HRT; Funding acquisition, IHW; Investigation, HRT, LMH; Methodology, THL, HRT, IHW; Project administration, IHW; Supervision, THL, IHW; Writing–original draft, HRT; Writing–review & editing, THL, LMH, IHW.

SUPPLEMENTARY MATERIALS

Supplementary materials can be found via https://doi.org/10.4235/agmr.25.0124.
Table S1.
Comparison of hospitalization costs of trauma patients by age group (<65 vs. ≥65 years)
agmr-25-0124-Table-S1.pdf
Table S2.
Comparison of hospitalization costs of trauma patients by age group (<65 vs. ≥65 years), stratified by mortality
agmr-25-0124-Table-S2.pdf
Table S3.
Univariate logistic regression of factors associated with mortality in young and elder adults
agmr-25-0124-Table-S3.pdf
Table S4.
Sex-specific distribution of older trauma patients
agmr-25-0124-Table-S4.pdf

Fig. 1.
Forest plot of the age-stratified predictors of in-hospital mortality among trauma patients. It shows adjusted odds ratios (aORs) and 95% confidence intervals for factors associated with in-hospital mortality among older and younger trauma patients. Red circles represent older patients (≥65 years) and blue circles represent younger patients (<65 years). Factors with aOR <1 indicate an association with lower odds of in-hospital mortality. Horizontal bars denote 95% confidence intervals. p-values are shown for each factor; aORs are plotted on a logarithmic scale. GCS, Glasgow Coma Scale; RTS, Revised Trauma Score; AIS, Abbreviated Injury Scale.
agmr-25-0124f1.jpg
Table 1.
Baseline and clinical characteristics of trauma patients by age group (<65 vs. ≥65 years)
Variable Overall (n=10,358) Younger group, <65 y (n=6,206) Geriatric group, ≥65 y (n=4,152) p-value
Demographics
 Age (y) 54.2±24.4 38.6±18.3 77.5±8.5 <0.001
 Male sex 5,409 (52.2) 3,844 (61.9) 1,565 (37.7) <0.001
Injury severity
 Glasgow Coma Scale <0.001
  ≤8 441 (4.3) 267 (4.3) 174 (4.2)
  9–12 343 (3.3) 157 (2.5) 186 (4.5)
  13–15 9,574 (92.4) 5,782 (93.2) 3,792 (91.3)
 Revised trauma score 7.5±1.2 7.5±1.3 7.6±1.1 0.006
 Injury severity score <0.001
  0–15 8,595 (83.0) 5,310 (85.5) 3,285 (79.1)
  16–24 1,116 (10.8) 532 (8.6) 584 (14.1)
  ≥25 647 (6.2) 364 (5.9) 283 (6.8)
Severe injury (Abbreviated Injury Scale ≥3)
 Head 1,726 (16.7) 793 (12.8) 933 (22.5) <0.001
 Face 39 (0.4) 34 (0.5) 5 (0.1) <0.001
 Thoracic 549 (5.3) 350 (5.6) 199 (4.8) 0.059
 Abdominal 231 (2.2) 165 (2.7) 66 (1.6) <0.001
 Extremities 3,728 (36.0) 1,721 (27.7) 2,007 (48.3) <0.001
 Appearance 65 (0.6) 43 (0.7) 22 (0.5) 0.303
Mechanism of injury
 Traffic 3,219 (31.1) 2,530 (40.8) 689 (16.6) <0.001
 Crush 683 (6.6) 572 (9.2) 111 (2.7) <0.001
 Fall 5,563 (53.7) 2,350 (37.9) 3,213 (77.3) <0.001
 Penetrating 417 (4.0) 373 (6.0) 44 (1.1) <0.001
 Suicide 191 (1.8) 170 (2.7) 21 (0.5) <0.001
 Burn 285 (2.8) 211 (3.4) 74 (1.8) <0.001
Operative department
 Neurosurgery 442 (4.3) 210 (3.4) 232 (5.6) <0.001
 Plastic 951 (9.2) 783 (12.6) 168 (4.0) <0.001
 Orthopedic 6,716 (64.8) 3,922 (63.2) 2,794 (67.3) <0.001
 Thoracic 168 (1.6) 103 (1.7) 65 (1.6) 0.710
 Others 199 (1.9) 148 (2.4) 51 (1.2) <0.001
 Number of interventions <0.001
  0 1,947 (18.8) 1,069 (17.2) 878 (21.1)
  1–2 8,224 (79.4) 4,996 (80.5) 3,228 (77.8)
  ≥3 187 (1.8) 141 (2.3) 46 (1.1)
Clinical outcomes
 Hospital days 8.5±13.0 7.3±11.8 10.5±14.3 <0.001
 Intensive care unit stay 1,995 (19.3) 964 (15.5) 1,031 (24.8) <0.001
 Complications 952 (9.2) 353 (5.7) 599 (14.4) <0.001
 Mortality 375 (3.6) 165 (2.7) 210 (5.1) <0.001
Total costsa) (USD) 3,349±7,450 2,985±6,620 3,886±8,502 <0.001

Values are presented as mean±standard deviation or number (%).

a)Missing data; values presented based on available cases; mortality indicates in-hospital mortality.

Table 2.
Baseline and clinical characteristics of trauma patients according to age group (<65 vs. ≥65 years), stratified by mortality
Variable Younger group, <65 y Geriatric group, ≥65 y
Survive (n=6,041) Death (n=165) p-value Survive (n=3,942) Death (n=210) p-value
Demographics
 Age (y) 38.5±18.4 42.8±15.9 0.003 77.4±8.5 79.1±8.3 0.007
 Male sex 3,727 (61.7) 117 (70.9) 0.016 1,431 (36.3) 134 (63.8) <0.001
Injury severity
 Glasgow Coma Scale <0.001 <0.001
  ≤8 128 (2.1) 139 (84.2) 67 (1.7) 107 (51.0)
  9-12 144 (2.4) 13 (7.9) 162 (4.1) 24 (11.4)
  13-15 5,769 (95.5) 13 (7.9) 3,713 (94.2) 79 (37.6)
 Revised trauma score 7.7±0.8 1.9±2.7 <0.001 7.7±0.6 5.1±3.0 <0.001
 Injury severity score <0.001 <0.001
  0-15 5,300 (87.7) 10 (6.1) 3,248 (82.4) 37 (17.6)
  16-24 523 (8.7) 9 (5.5) 542 (13.7) 42 (20.0)
  ≥25 218 (3.6) 146 (88.4) 152 (3.9) 131 (62.4)
Severe injury (Abbreviated Injury Scale ≥3)
 Head 685 (11.3) 108 (65.5) <0.001 777 (19.7) 156 (74.3) <0.001
 Face 32 (0.5) 2 (1.2) 0.241 4 (0.1) 1 (0.5) 0.127
 Thoracic 304 (5.0) 46 (27.9) <0.001 170 (4.3) 29 (13.8) <0.001
 Abdominal 150 (2.5) 15 (9.1) <0.001 61 (1.5) 5 (2.4) 0.347
 Extremities 1,701 (28.2) 20 (12.1) <0.001 1,975 (50.1) 32 (15.2) <0.001
 Appearance 35 (0.6) 8 (4.8) <0.001 10 (0.3) 12 (5.7) <0.001
Mechanism of injury
 Traffic 2,474 (41.0) 56 (33.9) 0.070 636 (16.1) 53 (25.2) 0.001
 Crush 569 (9.4) 3 (1.9) 0.001 110 (2.8) 1 (0.5) 0.043
 Fall 2,313 (38.3) 37 (22.4) <0.001 3,081 (78.2) 132 (62.9) <0.001
 Penetrating 367 (6.1) 6 (3.7) 0.193 43 (1.1) 1 (0.5) 0.397
 Suicide 113 (1.8) 57 (34.5) <0.001 13 (0.3) 8 (3.8) <0.001
 Burn 205 (3.4) 6 (3.6) 0.865 59 (1.5) 15 (7.1) <0.001
Operative department
 Neurosurgery 193 (3.2) 17 (10.3) <0.001 192 (4.9) 40 (19.0) <0.001
 Plastic 780 (12.9) 3 (1.8) <0.001 162 (4.1) 6 (2.9) 0.369
 Orthopedic 3,917 (64.8) 5 (3.0) <0.001 2,770 (70.3) 24 (11.4) <0.001
 Thoracic 99 (1.6) 4 (2.4) 0.436 59 (1.5) 6 (2.9) 0.122
 Others 136 (2.3) 12 (7.3) <0.001 46 (1.2) 5 (2.4) 0.120
 Number of interventions <0.001 <0.001
  0 941 (15.6) 128 (77.6) 744 (18.9) 134 (63.8)
  1–2 4,966 (82.2) 30 (18.2) 3,159 (80.1) 69 (32.9)
  ≥3 134 (2.2) 7 (4.2) 39 (1.0) 7 (3.3)
Clinical outcomes
 Hospital days 7.4±11.8 3.6±9.9 <0.001 10.3±13.9 13.1±20.0 0.007
 Intensive care unit stay 899 (14.9) 65 (39.4) <0.001 905 (23.0) 126 (60.0) <0.001
 Complications 321 (5.3) 32 (19.4) <0.001 507 (12.9) 92 (43.8) <0.001
Total costsa) (USD) 2,909±6,437 9,365±14,316 <0.001 3,547±7,433 11,758±20,141 <0.001

Values are presented as mean±standard deviation or number (%).

a)Missing data; values presented based on available cases.

Table 3.
Multivariable logistic regression of factors associated with in-hospital mortality in younger and geriatric adults
Outcome/variable Adjusted OR (95 % CI)a) p-value
Younger group, <65 y
 Age (y) 1.03 (1.01–1.04) 0.003
 Glasgow Coma Scale
  ≤8 14.10 (5.38–36.92) <0.001
  9–12 7.18 (2.88–17.91) <0.001
  13–15 Reference
 Revised trauma score 0.57 (0.49–0.65) <0.001
 Severe injury (AIS≥3)
  Thoracic 2.12 (1.11–4.06) 0.023
  Extremities 9.83 (3.64–26.52) <0.001
 Mechanism of injury
  Fall 3.25 (1.69–6.23) <0.001
  Suicide 3.61 (1.64–7.94) 0.001
 Operative department
  Neurosurgery 0.32 (0.15–0.68) 0.003
  Plastic 0.11 (0.02–0.53) 0.006
  Orthopedic 0.01 (0.004–0.06) <0.001
Geriatric group, ≥65 y
 Male sex 1.45 (1.01–2.07) 0.046
 Age (y) 1.04 (1.02–1.06) 0.001
 Glasgow Coma Scale
  ≤8 7.33 (3.69–14.57) <0.001
  9–12 1.67 (0.95–2.93) 0.072
  13–15 Reference
 Revised trauma score 0.73 (0.64–0.84) <0.001
 Severe injury (AIS≥3)
  Head 3.21 (1.90–5.44) <0.001
  Thoracic 2.02 (1.10–3.71) 0.023
  Extremities 4.82 (2.15–10.82) <0.001
  Appearance 15.08 (4.22–53.81) <0.001
 Mechanism of injury
  Burn 2.57 (1.004–6.57) 0.049
 Operative department
  Orthopedic 0.09 (0.04–0.21) <0.001
  Thoracic 0.21 (0.07–0.63) 0.005

AIS, Abbreviated Injury Scale.

a)Variables with p<0.15 in univariate analysis were included in the multivariable model, and backward selection using the likelihood ratio test was applied for variable selection. Injury severity score was excluded from the multivariable model due to collinearity with the severe injury variable.

REFERENCES

1. World Health Organization. Injuries and violence [Internet]. Geneva, Switzerland: World Health Organization; 2024 [cited 2025 Jan 25]. Available from: https://www.who.int/news-room/fact-sheets/detail/injuries-and-violence.

2. World Health Organization. Ageing and health [Internet]. Geneva, Switzerland: World Health Organization; 2024 [cited 2025 Jan 25]. Available from: https://www.who.int/news-room/fact-sheets/detail/ageing-and-health.

3. Crimmins EM. Trends in the health of the elderly. Annu Rev Public Health 2004;25:79-98.
crossref pmid
4. Ministry of the Interior Taiwan, Republic of China (Taiwan). Population statistics at the end of July 2025 [Internet]. Taipei, Taiwan: Ministry of the Interior; 2025 [cited 2025 Sep 4]. Available from: https://www.moi.gov.tw/News_Content.aspx?n=9&s=330504.

5. Ministry of the Interior, Republic of China (Taiwan). Average life expectancy [Internet]. Taipei, Taiwan: Ministry of the Interior; 2024 [cited 2025 Oct 8]. Available from: https://www.moi.gov.tw/News_Content.aspx?n=4&s=330934&utm_source.

6. Taiwan Ministry of Health and Welfare. The statistical results of causes of death for Taiwanese nationals in 2023 [Internet]. Taipei, Taiwan: Ministry of Health and Welfare; 2023;[cited 2025 Jan 25]. Available from: https://dep.mohw.gov.tw/DOS/cp-5339-59467-113.html.

7. de Vries R, Reininga IH, Pieske O, Lefering R, El Moumni M, Wendt K. Injury mechanisms, patterns and outcomes of older polytrauma patients: an analysis of the Dutch Trauma Registry. PLoS One 2018;13:e0190587.
crossref pmid pmc
8. Brown CV, Rix K, Klein AL, Ford B, Teixeira PG, Aydelotte J, et al. A comprehensive investigation of comorbidities, mechanisms, injury patterns, and outcomes in geriatric blunt trauma patients. Am Surg 2016;82:1055-62.
crossref pmid pdf
9. Adams SD, Holcomb JB. Geriatric trauma. Curr Opin Crit Care 2015;21:520-6.
crossref pmid
10. Grossman MD, Ofurum U, Stehly CD, Stoltzfus J. Long-term survival after major trauma in geriatric trauma patients: the glass is half full. J Trauma Acute Care Surg 2012;72:1181-5.
crossref pmid
11. Lee IY, Shih CY, Wei YT, Weng TC, Shieh SJ, Wang JD. Increasing burden of major trauma in elderly adults during 2003-2015: analysis of real-world data from Taiwan. J Formos Med Assoc 2022;121(1 Pt 1):144-51.
crossref pmid
12. Gioffre-Florio M, Murabito LM, Visalli C, Pergolizzi FP, Fama F. Trauma in elderly patients: a study of prevalence, comorbidities and gender differences. G Chir 2018;39:35-40.
crossref pmid pmc
13. Kocuvan S, Brilej D, Stropnik D, Lefering R, Komadina R. Evaluation of major trauma in elderly patients: a single trauma center analysis. Wien Klin Wochenschr 2016;128(Suppl 7):535-42.
crossref pmid pdf
14. Bendinelli C, Ku D, King KL, Nebauer S, Balogh ZJ. Trauma patients with prehospital Glasgow Coma Scale less than nine: not a homogenous group. Eur J Trauma Emerg Surg 2020;46:873-8.
crossref pmid pdf
15. Champion HR, Sacco WJ, Copes WS, Gann DS, Gennarelli TA, Flanagan ME. A revision of the trauma score. J Trauma 1989;29:623-9.
crossref pmid
16. Kojima M, Endo A, Shiraishi A, Otomo Y. Age-related characteristics and outcomes for patients with severe trauma: analysis of Japan’s nationwide trauma registry. Ann Emerg Med 2019;73:281-90.
crossref pmid
17. Adams SD, Cotton BA, McGuire MF, Dipasupil E, Podbielski JM, Zaharia A, et al. Unique pattern of complications in elderly trauma patients at a Level I trauma center. J Trauma Acute Care Surg 2012;72:112-8.
crossref pmid
18. Hashmi A, Ibrahim-Zada I, Rhee P, Aziz H, Fain MJ, Friese RS, et al. Predictors of mortality in geriatric trauma patients: a systematic review and meta-analysis. J Trauma Acute Care Surg 2014;76:894-901.
crossref pmid
19. Keller JM, Sciadini MF, Sinclair E, O'Toole RV. Geriatric trauma: demographics, injuries, and mortality. J Orthop Trauma 2012;26:e161-5.
crossref pmid
20. Coleman JR, Moore EE, Samuels JM, Cohen MJ, Sauaia A, Sumislawski JJ, et al. Trauma resuscitation consideration: sex matters. J Am Coll Surg 2019;228:760-8.e1.
crossref pmid pmc
21. Bin Kunji Mohamad MI, Jamaluddin SF, Ahmad N, Bahar A, Khalid ZM, Binti Mohd Zaki NA, et al. Trauma outcomes differences in females: a prospective analysis of 76 000 trauma patients in the Asia-Pacific region and the contributing factors. Scand J Trauma Resusc Emerg Med 2025;33:34.
crossref pmid pmc
22. Kondo Y, Miyazato A, Okamoto K, Tanaka H. Impact of sex differences on mortality in patients with sepsis after trauma: a nationwide cohort study. Front Immunol 2021;12:678156.
crossref pmid pmc
23. World Health Organization. Road traffic injuries [Internet]. Geneva, Switzerland: World Health Organization; 2023 [cited 2025 Oct 10]. Available from: https://www.who.int/news-room/fact-sheets/detail/road-traffic-injuries/?utm_source.

24. Koch DA, Becker L, Schweigkofler U, Hagebusch P, Faul P, Waydhas C, et al. Undertriage in geriatric trauma: insights from a multicentre cohort study. Scand J Trauma Resusc Emerg Med 2025;33:123.
crossref pmid pmc pdf
25. Kim S, Kim S, Woo S, Oh J, Son Y, Jacob L, et al. Temporal trends and patterns in mortality from falls across 59 high-income and upper-middle-income countries, 1990-2021, with projections up to 2040: a global time-series analysis and modelling study. Lancet Healthy Longev 2025;6:100672.
crossref pmid
26. Gowing R, Jain MK. Injury patterns and outcomes associated with elderly trauma victims in Kingston, Ontario. Can J Surg 2007;50:437-44.
pmid pmc
27. Stanojcic M, Chen P, Xiu F, Jeschke MG. Impaired immune response in elderly burn patients: new insights into the immune-senescence phenotype. Ann Surg 2016;264:195-202.
crossref pmid
28. Cords CI, van Baar ME, Pijpe A, Nieuwenhuis MK, Bosma E, Verhofstad MH, et al. Short-term and long-term increased mortality in elderly patients with burn injury: a national longitudinal cohort study. BMC Geriatr 2023;23:30.
crossref pmid pmc pdf
29. Romanowski KS, Barsun A, Pamlieri TL, Greenhalgh DG, Sen S. Frailty score on admission predicts outcomes in elderly burn injury. J Burn Care Res 2015;36:1-6.
crossref pmid
30. Javali RH, Patil A, Srinivasarangan M. Comparison of injury severity score, new injury severity score, revised trauma score and trauma and injury severity score for mortality prediction in elderly trauma patients. Indian J Crit Care Med 2019;23:73-7.
crossref pmid pmc
31. Simunovic N, Devereaux PJ, Sprague S, Guyatt GH, Schemitsch E, Debeer J, et al. Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analysis. CMAJ 2010;182:1609-16.
crossref pmid pmc
32. Gonul R, Tasar PT, Tuncer K, Karasahin O, Binici DN, Sevinc C, et al. Mortality-related risk factors in geriatric patients with hip fracture. Ann Geriatr Med Res 2023;27:126-33.
crossref pmid pmc pdf
33. Heiden JJ, Goodin SR, Mormino MA, Siebler JC, Putnam SM, Lyden ER, et al. Early ambulation after hip fracture surgery is associated with decreased 30-day mortality. J Am Acad Orthop Surg 2021;29:e238-42.
crossref pmid
34. Lei YT, Xie JW, Huang Q, Huang W, Pei FX. Benefits of early ambulation within 24 h after total knee arthroplasty: a multicenter retrospective cohort study in China. Mil Med Res 2021;8:17.
crossref pmid pmc pdf
35. Liao J, Qi Z, Chen B, Lei P. Association between early ambulation exercise and short-term postoperative recovery after open transforaminal lumbar interbody fusion: a single center retrospective analysis. BMC Musculoskelet Disord 2023;24:345.
crossref pmid pmc pdf
36. Holcomb JB, McMullin NR, Kozar RA, Lygas MH, Moore FA. Morbidity from rib fractures increases after age 45. J Am Coll Surg 2003;196:549-55.
crossref pmid
37. De Simone B, Chouillard E, Podda M, Pararas N, de Carvalho Duarte G, Fugazzola P, et al. The 2023 WSES guidelines on the management of trauma in elderly and frail patients. World J Emerg Surg 2024;19:18.
crossref pmid pmc
38. Kao CC, Chen KC, Chiang XH, Chuang JH, Lu CW, Hsiao WL, et al. Clinical outcomes of rib fracture stabilization and conservative treatment in a high-volume Asian trauma center: a propensity score-matched retrospective study. World J Emerg Surg 2025;20:40.
crossref pmid pmc pdf
39. Ang BH, Chen WS, Lee SWH. Global burden of road traffic accidents in older adults: a systematic review and meta-regression analysis. Arch Gerontol Geriatr 2017;72:32-8.
crossref pmid
40. Mulvey HE, Haslam RD, Laytin AD, Diamond CA, Sims CA. Unplanned ICU admission is associated with worse clinical outcomes in geriatric trauma patients. J Surg Res 2020;245:13-21.
crossref pmid


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