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Journal of the Korean Geriatrics Society 2007;11(3):111-116.
Published online September 30, 2007.
Multicenter Investigation on Clinical Characteristics, Cognitive Impairments, Behavioral and Psychological Symptoms of Demented Elderly in Busan-Gyeongnam Province
Kyung Won Park, Hyun Sook Kim, Jae Woo Kim, Soo Young Kim, Eung Gyu Kim, Tae You Kim, Sang Min Sung, Taehong Sohn, Bong Goo, Soo Jin Yoon, Sung Min Yoon, Sang Chan Lee, Mun Seong Choi, Tae Yong Hong
1Department of Neurology, Dong-A University College of Medicine, Busan, Korea. neuropark@dau.ac.kr
2Department of Social Welfare, Kyungsung University, Busan, Korea.
3Department of Neurology, Inje University College of Medicine, Busan, Korea.
4Department of Neurology, Willis Hospital, Busan, Korea.
5Department of Neurology, Busan Medical Center, Busan, Korea.
6The Institute for East Asian Studies in Don-A Univertisy, Busan, Korea.
7Department of Neurology, Kosin University College of Medicine, Busan, Korea.
8Department of Neurology, Eulji University Hospital, Daejeon, Korea.
9Department of Neurology, Samil Jeongpoong Hospital, Masan, Korea.
10Department of Neurology, Dong-eui Medical Center, Busan, Korea.
11Department of Neurology, Maryknoll Hospital, Busan, Korea.
12Department of Neurology, Gimhae Hansol Hospital, Gimhae, Korea.
부산, 경남지역 치매 노인의 임상적 특성과 인지장애 및 행동심리 증상에 관한 다기관 조사 연구
Abstract
OBJECTIVES: The purpose of this study is to examine the state of demographic findings with clinical characteristics, cognitive impairment and behavioral psychological symptoms of demented elderly in Busan-Gyeongnam Province.
METHODS
Patients with dementia who were registered at nine medical centers in Busan Metropolitan City and Gyeongnam Province were the major subjects of this study. Data was collected by face-to-face interview. The final sample consisted of 144 cases after eliminating several incomplete questionnaires. Based on the collected data, the authors evaluated demographic findings, clinical characteristics, and cognitive impairment and behavioral psychological symptoms of the patients with dementia using statistical analyses. All of the patients were taken the Korean version of Mini-Mental State Examination(K-MMSE), the Clinical Dementia Rating Scale(CDR) and the the Korean version of Neuropsychiatric Inventory(K-NPI).
RESULTS
Approximately 61% of the patients with dementia in Busan-Gyeongnam Province were women, and their mean age was 72.9(SD=8.3) years old. Their average education level was 2.3(SD=1.3) years. Among the demented elderly, Alzheimer's disease accounted for 68% compared with vascular dementia(32%) and the proportion of mild stage of dementia was above 50%. The mean K-MMSE score was 16.7(SD=6.2), the mean CDR score was 1.3(SD=0.8), and the Barthel Index with K-IADL score were 16.7(SD=5.4) and 1.5(SD=0.9). The average score of K-NPI was 22.6(SD=22.5) and the number of manifested K-NPI was 4.9(SD=2.8). The K-NPI score has increased in demented elderly as the severity of dementia getting worse according to the CDR score. The number of manifested K-NPI was significantly more prevalent in patients with AD than that of patients with VD.
CONCLUSION
This study is a meaningful approach to the state of demographic findings, clinical characteristics, cognitive impairment and behavioral psychological symptoms associated with the dementied elderly who were comprehensively examined in Busan-Gyeongnam Province. Based on this study, we found that the demographic information was comparable with other epidemiologic study in Korea and our study patients were relatively mild stage of demenitia according to the assessment of cognition and behavioral symptom scales.
Key Words: Dementia, Alzheimer's disease, Vascular dementia, Cognitive impairments, Behavioral and psychological symptoms
초 록
결론적으로, 본 연구를 통해 부산, 경남지역에 거주하는 치매 노인들 중 병원에서 치매 진단을 받고, 약물치료와 함께 정기적인 관찰을 받고 있는 환자들에 대한 인구사회학적 특성과 함께 전반적인 임상적 특징을 파악할 수 있었고, 인지기능장애 상태와 행동심리 증상의 정도를 종합적으로 분석하였다는 점에서 중요한 의의를 찾을 수 있다.
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