Clinical Characteristics and Outcomes of Geriatric Patients in Upper Gastrointestinal Bleeding |
Ki Sang Lee, Soong Lee, Seung Chul Pack, Hyeon Min Lee, Jae Kyu Lim, David Hwang, Seong Il Park, Hoon Kang, Sung Kyu Choi |
Department of Internal Medicine, Seonam University College of Medicine, Gwangju, Korea. anthemlove@naver.com |
상부 위장관 출혈을 보인 노인환자의 임상적 특성 |
이기상, 이숭, 백승철, 이현민, 임재규, 황다윗, 박성일, 강훈, 최성규 |
서남대학교 의과대학 내과학 교실 |
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Abstract |
BACKGROUND The incidence of upper gastrointestinal bleeding has decreased in the general population but has increased in geriatric patients worldwide. The aim of this study was to evaluate the clinical characteristics and outcomes of geriatric patients (aged 65 or older) with upper gastrointestinal bleeding and to compare them with non-geriatric patients (less than 65 years old). METHODS We conducted a retrospective study of 288 patients with upper gastrointestinal bleeding from January 2007 to August 2010. We compared the clinical characteristics and outcomes of geriatric patients (n=148, 51.4%) with those of non-geriatric patients (n=140, 48.6%). RESULTS Cardiovascular disease, hypertension, and cerebrovascular accidents were more prevalent in the geriatric group, compared with those in the non-geriatric group (p<0.05). Vital signs were more unstable in the geriatric group than those in the non-geriatric group (p<0.05). The geriatric group had taken more ulcerogenic drugs than those in the non-geriatric group (p<0.05). The most common cause of upper gastrointestinal bleeding was peptic ulcer (72.3%) in the geriatric group, whereas it was variceal bleeding (41.4%) in the non-geriatric group. Treatment methods, transfusion volume, operation rate, and mortality were not different between the two groups. The length of hospital stay and length of intensive care unit (ICU) stay were significantly longer in geriatric patients than those in the non-geriatric group (p<0.05). CONCLUSION Geriatric patients with upper gastrointestinal bleeding had longer ICU and hospital stays than those of non-geriatric patients. Important emerging etiologies such as ulcerogenic drugs and associated chronic illness should be monitored and treated early in these patients. |
Key Words:
Upper gastrointestinal bleeding, Geriatrics, Chronic illness, Ulcerogenic drugs |
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