A Case of Vertebral Osteomyelitis With Epidural Abscess Caused by Mycobacterium intracellulare in a Rheumatoid Arthritis Patient |
Hae Su Kim, Jieun Kim, Jeong Im Choi, Hye Jin Yoon, Jae Ha Kim, You Shin Kim, Dong Shin Kwak, Jung Kyu Lee, Seunghun Lee, Hyunjoo Pai |
1Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. paihj@hanyang.ac.kr 2Department of Radiology, Hanyang University College of Medicine, Seoul, Korea. |
류마티스관절염 환자에서 발생한 Mycobacterium intracellulare에 의한 경막외 농양을 동반한 척추골수염: 증례보고 및 문헌고찰 |
김해수1, 김지은1, 최정임1, 윤혜진1, 김재하1, 김유신1, 곽동신1, 이정규1, 이승훈2, 배현주1 |
1한양대학교 의과대학 내과학교실, 2한양대학교 의과대학 방사선과교실 |
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Abstract |
Mycobacterium avium complex (MAC) is the most common pathogen in nontuberculous mycobacterial lung diseases, but vertebral osteomyelitis caused by MAC is rare. We experienced a case of vertebral osteomyelitis with epidural abscess in a rheumatoid arthritis patient who received immunosuppressive agents. Initial assessment was tuberculous vertebral osteomyelitis, and then treated with antituberculous drugs. Fifty-six days later, Mycobacterium intracellulare was identified from abscess culture and drugs were altered to clarithromycin, rifabutin, and ethambutol. After 3 months of M. intracellulare treatment, the radiological findings showed increases of epidural abscess. According to the suseptibility, the patient received intravenous amikacin for four weeks, and then, oral ciprofloxacin in addition to clarithromycin, rifabutin, and ethambutol. The patient is being treated with the medication for 13 months and currently showing slow improvements. |
Key Words:
Mycobacterium intracellulare, Nontuberculous mycobacteria, Osteomyelitis |
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