| A Case of Demyelinating Peripheral Neuropathy Associated with Hashimoto's Thyroiditis |
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Jung Hwan Park, Sang Mo Hong, Chang Bum Lee, Yong Soo Park, Dong Sun Kim, Woong Hwan Choi, You Hern Ahn |
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Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. ahnyh@hanyang.ac.kr |
| 하시모토 갑상샘염과 연관된 말이집탈락 말초 신경병증 1례 |
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박정환1, 홍상모1, 이창범1, 박용수1, 김동선1, 최웅환1, 안유헌1 |
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한양대학교 의과대학 내과학교실 |
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| Abstract |
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Peripheral neuropathy is somewhat common in hypothyroidism. But, demyelinating peripheral neuropathy in Hashimoto's thyroiditis is extremely rare. The pathophysiology of demyelinating peripheral neuropathy associated with Hashimoto's thyroiditis is unclear and complex and various mechanisms including the cell mediated and antibody mediated responses may be operative. We report a 68-year-old woman who presented with paresthesia and gait disturbance. She was diagnosed with hypothyroidism 7 years prior and has been on thyroid hormone. Serum antithyroglobulin antibody was significantly elevated. Nerve conduction studies revealed sensory-motor demyelinating polyneuropathy with prolonged distal latencies and reduced conduction velocities. She was under the suspicion of the lymphoma of thyroid. Surgery was performed which turned up to be Hashimoto's thyroiditis. With the impression of rare demyelinating peripheral neuropathy associated with Hashimoto's thyroiditis after other causes were excluded, she was treated with steroid which ameliorated rapidly her neurological symptoms. |
| Key Words:
Hashimoto's thyroiditis, Polyradiculoneuropathy, Steroids |
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