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Ann Geriatr Med Res  <  Volume 23(1); 2019 <  Articles

Ann Geriatr Med Res 2019; 23(1): 38-41  https://doi.org/10.4235/agmr.19.0005
Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation
Sun-Hyung Kim, Deok Su Sin , Jae-Young Lim
Department of Rehabilitation Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine,
Seongnam, Korea
Correspondence to: Deok Su Sin, M, https://orcid.org/0000-0001-5920-6925
Department of Rehabilitation Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam 13620, Korea, E-mail: plexion0202@gmail.com
Received: January 21, 2019; Revised: March 19, 2019; Accepted: March 20, 2019; Published online: March 31, 2019.
© The Korean Geriatrics Society. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elevation of inflammatory markers was also revealed. We assumed that chronic low-grade inflammation with aging, also called “inflammaging,” contributed to the development of multiple comorbidities. After multidisciplinary treatment and comprehensive rehabilitation, he could ambulate again with minimal to moderate assistance. Various age-related disorders should be suspected when older patients present with chronic low-grade inflammation.
Keywords: Inflammation, Sarcopenia, Alzheimer disease


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