Ann Geriatr Med Res 2017; 21(3): 138-141  http://dx.doi.org/10.4235/agmr.2017.21.3.138
Primary Sclerosing Cholangitis in an Elderly Patient: A Diagnostic Challenge
Tobar-Marcillo Marco1,2, Vela-Vizcaino Hiram1,2, Pliego-Reyes Lenin1,2
1Department of Internal Medicine, Regional Hospital “Licenciado Adolfo Lopez Mateos, Institute for Social Security and Services for State Workers", Mexico City, 2National Autonomous University of Mexico, School of Medicine, Mexico City, Mexico
Correspondence to: Tobar-Marcillo Marco
National Autonomous University of Mexico, School of Medicine, Avenida Gabriel Mancera 1258, Colonia del Valle, Delegation Benito Juarez, Mexico City 03100, Mexico
Tel: +521-5566540252 Fax:+521-56614469 E-mail: marcotobar1@hotmail.com
Received: May 24, 2017; Revised: August 27, 2017; Accepted: September 1, 2017; Published online: September 30, 2017.
© The Korea Geriatrics Society. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Jaundice syndrome is a diagnostic challenge for physicians. It must be diagnosed based on its etiology, which depends on liver function test results, clinical manifestations, and age of presentation, and the objective is to rule out the most common causes and then the rare causes. We describe the case of a male patient aged 86 years who had jaundice and was diagnosed as having primary sclerosing cholangitis based on liver biopsy findings. It is a chronic, progressive cholestatic liver disease with unknown etiology until now. Primary sclerosing cholangitis is characterized by inflammation, fibrosis, and stenosis of small, medium, and large intrahepatic and extrahepatic biliary ducts. Although it is a rare entity in geriatric patients, certain characteristics are infrequently considered in clinical practice; thus, considering all characteristics of this disease would help physicians make the diagnosis earlier. It is a condition that should be considered when jaundice is associated with pruritus and elevated levels of peripheral eosinophils and immunoglobulin E.
Keywords: Cholangitis, Sclerosing, Jaundice, Elderly


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