| A Multicenter Study on the Tetanus Antibody Titers of Elderly Koreans |
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Jong Hwan Shin, Chang Je Park, Jin Joo Kim, Jin Seong Cho, Seung Chul Lee, Ji Ho Ryu, Ki Yoel Kim, Hui Jai Lee, Young Joon Kang, Won Chul Cha |
1Department of Emergency Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea. skyshin1@dreamwiz.com
2Department of Emergency Medicine, Gachon University Gil Hospital, Incheon, Korea.
3Department of Emergency Medicine, Dongguk University Ilsan Hospital, Ilsan, Korea.
4Department of Emergency Medicine, Pusan National University Yangsan Hospital, Busan, Korea.
5Department of Emergency Medicine, Konkuk University Chungju Hospital, Chungju, Korea.
6Department of Emergency Medicine, Wonju Medical Center, Wonju, Korea.
7Department of Emergency Medicine, Jeju National University Hospital, Jeju, Korea.
8Department of Emergency Medicine, Seogwipo Medical Center, Jeju, Korea. |
| 60세 이상의 한국인 파상풍 항체 역가 다기관 조사 |
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신종환1,박창제1,김진주2,조진성2,이승철3,류지호4,김기열5,이휘재6,강영준7,차원철8 |
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서울대학교병원운영 서울특별시 보라매병원 응급의학과1, 가천의대 길병원 응급의학과2, 동국대학교 일산병원 응급의학과3, 양산부산대학교병원 응급의학과4, 건국대학교 충주병원 응급의학과5, 원주의료원 응급의학과6, 제주대학교병원 응급의학과7, 서귀포의료원 응급의학과8 |
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| Abstract |
BACKGROUND
Although tetanus infections have diminished dramatically since the advent of tetanus vaccination, this disease has not disappeared. Those 60 years and older are still very much at risk for this infection. Thus, we investigated the tetanus antibody titers in people 60 years and older in Korea.
METHODS
Our subjects included those visiting eight emergency departments from March 2009 to February 2010 after an injury with stable vital signs and without acute disease. Samples obtained were tested using the tetanus immunoglobulin enzyme-linked immunosorbent assay method. The resultant tetanus antibody titers were analyzed.
RESULTS
The number of subjects enrolled was 462. The mean titer was 0.09+/-0.14 IU/mL. Twenty-two percent of the subjects had a safe titer level (>0.1 IU/mL). Males and urban subjects had higher tetanus antibody titers than did females and suburban subjects. Subjects living in Incheon, Gangwon-do, Chungcheong-do, and Jeju-do had lower titers.
CONCLUSION
The results of this study showed that Koreans 60 years and older did not have a protective mean level of tetanus antibody titer and that 78% of the subjects did not have a seroprotective level after tetanus exposure. Therefore, a national effort to administer tetanus vaccination to elderly Koreans is needed. |
| Key Words:
Tetanus, Elderly, Korea |
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